"Step-off" vertebral body: Gaucher's disease versus sickle cell hemoglobinopathy

Sickle cell hemoglobinopathy protection against malaria: is it changing?

Sickle cell hemoglobinopathy Malaria Severity

Intracardiac Thrombosis in Sickle Cell Disease

In patients with sickle cell disease, thrombotic microangiopathy is a rare complication. Also in sickle cell disease, intracardiac thrombus formation without structural heart diseases or atrial arrhythmias is a rare phenomenon. We herein describe a 22-year-old woman, who was a known case of sickle cell-βthalassemia, had a history of recent missed abortion, and was admitted with a vaso-occlusive...

Open heart surgery in patients with sickle cell hemoglobinopathy.

BACKGROUND In patients with sickle cell trait or disease, reduced life expectancy and a tendency for complications are believed to negatively affect likelihood of survival after open heart surgery. The aim of this study was to review retrospectively the perioperative results of patients undergoing cardiac surgery at our institution. METHODS AND RESULTS Between January 1995 and December 2006, ...

An unusual type of hemoglobinopathy resembling sickle cell-thalassemia disease in a Jamaican family.

Standard hematologic methods were used.2 In vitro sickling tests were carried out using the method of 1)aiand and Castle.’ Fetal hemoglobin was estimated by the alkali denaturation technic of Singer, Chernoff and Singer.’ Filter-paper electrophoresis of hemoglobin was performed in a horizontal tank using barbitone buffer pH 8.6 and ionic strength about 0.02. The technic is described in detail e...

Sickle cell disease: a step closer to the dream.